Aortic 4D flow: quantifying the effects of contrast and field strength at 1.5 T, 3T and 7T

نویسندگان

  • Aaron T Hess
  • Malenka M Bissell
  • Andrew Lewis
  • Ntobeko A Ntusi
  • Jane M Francis
  • Saul G Myerson
  • Stefan Neubauer
  • Matthew D Robson
چکیده

Background 4D flow is a promising new method for assessment of aortic pathology, but is limited by signal-to-noise ratio (SNR) leading to long acquisition times. Higher field strength may prove a solution. SNR in aortic 4D flow increases at 3T versus 1.5T (Strecker et al, JMRI 2012) and further by adding a contrast agent (Bock et al, MRM 2010). This work extends this comparison to human 7 Tesla and quantifies the field strength dependent effects of contrast agents.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Improved depiction of hemodynamics in intracranial aneurysms by 4D flow MRI at 7T compared to 3T

Background Intracranial aneurysms are life threatening conditions and occur in 3-6% of the population. The annual rupture rate is approximately 2% associated with significant morbidity and mortality. Hemodynamic information obtained by 4D flow MRI may contribute to the assessment of rupture risk of intracranial aneurysms. However, the small sizes of intracranial aneurysms require high spatial r...

متن کامل

Cortical thickness determination of the human brain using high resolution 3 T and 7 T MRI data

PURPOSE The analysis of the human cerebral cortex and the measurement of its thickness based on MRI data can provide insight into normal brain development and neurodegenerative disorders. Accurate and reproducible results of the cortical thickness measurement are desired for sensitive detection. This study compares ultra-high resolution data acquired at 7T with 3T data for determination of the ...

متن کامل

Assessing functional connectivity measures at 3T and 7T

Introduction: Functional connectivity, implied by inter-region correlation, has previously been reported in spontaneous resting state BOLD activity. Previous work has shown high correlation between BOLD fMRI signals from functionally related disparate brain regions e.g. 1 implying that brain activity in these regions is connected even in the absence of external stimuli. It is well known that as...

متن کامل

The relationship between 7T fMRI BOLD and MEG derived γ activity

Introduction: The move to high field imaging is thought to be very beneficial for fMRI, promising an improved signal to noise ratio and increased BOLD contrast alongside increased spatial specificity [1]. It has been shown that the field strength dependence of the fractional signal change varies depending on the relative contributions of capillary and non-capillary venous vessels, with an incre...

متن کامل

3DQRS: a method to obtain reliable QRS complex detection within high field MRI using 12-lead electrocardiogram traces.

PURPOSE To develop a technique that accurately detects the QRS complex in 1.5 Tesla (T), 3T, and 7T MRI scanners. METHODS During early systole, blood is rapidly ejected into the aortic arch, traveling perpendicular to the MRI's main field, which produces a strong voltage (V(MHD)) that eclipses the QRS complex. Greater complexity arises in arrhythmia patients, since V(MHD) varies between sinus...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2014